Health

Flavonoid-rich Meals and Beverages Reduce Type 2 Diabetes Risk by 28%

Published

6 months ago

May 31, 2024

Arsi2021

Flavonoid-rich Meals and Beverages Reduce Type 2 Diabetes Risk by 28%

(CTN News) – The link between a diet high in flavonoids and the development of type 2 diabetes in a large British population was the subject of a recent research published in the Nutrition & Diabetes Trusted Source journal.

Existing evidence shows a reduced risk of type 2 diabetes in those who eat a plant-based diet. However, plants contain a wide variety of polyphenolic chemicals, and these compounds have varying bioavailability and bioactivity.

Isoflavones, flavanones, flavones, anthocyanins, and flavan-3-ols are the six primary subclasses of flavonoids, a class of polyphenolic chemicals. Some research suggests that increasing flavonoid consumption may improve insulin sensitivity and blood lipid profiles (Trusted Source).

Linking flavonoid consumption to the development of type 2 diabetes

From 2006 to 2010, more than half a million individuals in the United Kingdom were enrolled in the massive UK Biobank project, which provided the participants for the new research. The sample size was 113,097.

Two or more 24-hour dietary questionnaires were used to measure the individuals’ flavonoid consumption, which was then analyzed using the United States Department of Agriculture databases.

Ten foods were selected for their daily flavonoid content. By adding together the servings of these 10 items, a Flavodiet Score (FDS) was determined. To evaluate the association between flavonoid consumption in the diet and the onset of type 2 diabetes, statistical analyses were conducted, taking into consideration possible confounders.

Those who were older, more physically active, more educated, and female tended to eat more foods rich in flavonoids than younger, less educated, or younger participants.

An average of 805.7 mg of flavonoids were taken each day. With 67% and 22% of the total intake of the flavonoid subclasses, the most important components were polymers (including proanthocyanidins) and flavan-3-ols.

These categories were mostly derived from tea. The consumption of flavones, mostly found in peppers, was the lowest among all flavonoids. Researchers controlled for demographic and lifestyle variables in their analysis of the flavonoid intake type 2 diabetes risk connection.

The study indicated that the risk of acquiring type 2 diabetes was 28% lower in those with a higher Flavodiet Score (FDS), which is the same as eating six servings of foods rich in flavonoids per day, compared to those with a lower FDS, which is the same as eating one serving of flavonoids per day.

According to the study, a 6% reduction in diabetes risk was found for every serving of flavonoid-rich foods consumed daily; a 21% reduction in risk was associated with 4 servings of black or green tea daily; a 15% reduction in risk was associated with 1 serving of berries daily; and a 12% reduction in risk was associated with 1 serving of apples daily.

The anti-inflammatory and blood sugar-regulating properties of flavonoids

The probable mediators discovered in the investigation were insulin-like growth factor 1 (IGF-1), urate, cystatin C, body mass index (BMI), GGT, and ALT.

According to the results, a diet high in flavonoids may help with weight loss, inflammation, glucose metabolism, and kidney and liver health, all of which lead to a lower chance of developing type 2 diabetes.

The most common types of flavonoids are anthocyanins, flavan-3-ols, and flavonols; they improve glucose transport and metabolism and increase insulin production and signaling.

Because the participants were middle-aged Britons, it’s possible that the results won’t apply to those outside of Europe. Two specialists not associated with this study discussed the results with Medical News Today.

This study lends credence to many of our hypotheses on the etiology of type 2 diabetes, according to Megan Hilbert, RDN, a registered dietitian who focuses on nutrition for gut health and the gut-brain axis, who spoke with MNT.

Flavonoids have anti-inflammatory and weight-maintenance properties, and “this study confirms flavonoids’ impact on this,” she said. “These findings demonstrate that consuming flavonoids can lead to a decrease in excess adipose tissue, which can have pro-inflammatory effects, and in the adipose tissue surrounding smooth muscle tissue, which allows for increased absorption of blood glucose by these muscle cells,” Hilbert noted. These changes enhance the body’s ability to absorb blood glucose more efficiently, lowering the chance of developing type 2 diabetes.

According to Kelsey Costa, MS, RDN, creator of Dietitian Insights and a registered dietitian nutritionist, “the results of the present study are not surprising given flavonoids’ well-documented anti-diabetic effects” (Trusted Source). Costa posits that the association between flavonoids and a reduced risk of diabetes could be due to their function in blood sugar regulation:

She did warn that there was more data to suggest that flavonoids may have a preventive function in warding off type 2 diabetes, thanks to the big UK Biobank cohort and extensive follow-up.

Reasons why alcohol usage must be controlled

Further, she brought attention to the fact that “researchers are finding more and more evidence of the negative consequences of alcohol use, such as its link to obesity, insulin resistance, and other metabolic disorders that can lead to type 2 diabetes.”

Costa informed us that the study considered the participants’ total alcohol intake when examining the link between flavonoid consumption and type 2 diabetes risk. They then reanalyzed the data by removing red wine from the flavonoid diet score to see if the results would differ. Overall, they made a good call.

Aside from that, she said, “[t]his approach allowed them to isolate the effects of flavonoids without the influence of alcohol and show that the protective association between flavonoid intake and type 2 diabetes risk remained significant without any red wine consumption.”

Serious consequences for people’s health and the general population

Costa said people may improve their health and reduce their risk of chronic diseases without drinking too much alcohol if they eat a diet high in naturally occurring flavonoids from foods like fruits, vegetables, and teas.

Patients are encouraged to eat more foods high in flavonoids, as this may greatly lower their chance of developing type 2 diabetes. Consuming six servings of a mix of flavonoid-rich foods, including grapes, oranges, grapefruit, sweet peppers, onions, at least 70% dark chocolate, and notably black and green tea, apples, and berries, are among the attainable targets identified by the research, according to Costa.

The significance of incorporating flavonoid-rich foods into a well-rounded, health-promoting lifestyle is highlighted in these guidelines, which provide practical measures for enhancing health, even though further study is needed, she noted. “Although further research is required to determine which foods are best for preventing diabetes or how much of them to eat, there is little doubt that eating foods that are high in flavonoids on a regular basis can have important positive effects on health.”

“Even as the science continues to evolve,” Costa said, “this approach allows individuals to take proactive steps to enhance their well-being.”

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Health

Report Causes Pfizer Stock to Climb Approximately $1 Billion Acquired by Starboard

Published

2 months ago

October 7, 2024

Salman

(VOR News) – According to a rumor that activist investor Pfizer Starboard Value has taken a holding in the struggling pharmaceutical business that is expected to be worth around one billion dollars, the stock of Pfizer (PFE) is on the increase in premarket trading on Monday.

This comes after the report was made public. The report was made available to the general public following this. Starboard Value was successful in moving forward with the acquisition of the position.

Starboard is said to have approached Ian Read, a former chief executive officer of Pfizer, and Frank D’Amelio, a former chief financial officer, in order to seek assistance with its goals of boosting the performance of the company, according to the Wall Street Journal. Read and D’Amelio are both former Pfizer executives.

The purpose of this is to facilitate the accomplishment of its objectives, which include enhancing the overall performance of the firm.

In their previous jobs, D’Amelio and Read were chief financial officers.

It is stated in the report that the hedge fund is of the opinion that Pfizer, which is currently being managed by Albert Bourla, who succeeded Read as Chief Executive Officer (CEO) in 2019, does not demonstrate the same level of mergers and acquisitions (M&A) discipline that Read did. Bourla took over for Read in 2019. Read was succeeded by Bourla in the year 2019.

Pfizer, a multinational pharmaceutical conglomerate, has made substantial investments in the acquisition of more companies that are involved in the research and development of cancer medicines.

These businesses have been acquired for billions of dollars. The biotechnology company Seagen, which was acquired by Pfizer in the previous year for a price of $43 billion, is included in this category. One of the businesses that can be classified as belonging to this category is Seagen.

In spite of the fact that the S&P 500 Index experienced a 21% increase in 2024.

No major trading occurred in Pfizer stock that year.

Due to the fact that the demand for Pfizer’s COVID-19 vaccines fell after the firm reached its pandemic peak in 2021, the share price of the corporation has decreased by over fifty percent since that time.

This drop has occurred ever since the company’s shares reached their maximum peak, which was during the time that this decline occurred. Not only have they not changed at all, but they have also remained essentially stable. This is in contrast to the S&P 500, which has gained 21% since the beginning of this year.

Recently, the corporation was forced to take a hit when it decided to recall all of the sickle cell illness medications that it had distributed all over the world.

Fears that the prescription could lead patients to experience severe agony and possibly even death were the impetus for the decision to recall the product. In spite of the fact that Pfizer’s stock is increasing by almost three percent as a result of the news that followed the company’s decision, this is the circumstance that has come about.

SOURCE: IPN

Health

New Study Reveals Drinking Soda Pop Increases the Risk of Stroke

Published

2 months ago

October 6, 2024

VORNews

If you drink too much soda, fruit juice and coffee, beware!

A recent report from global research indicates that excessive consumption of coffee or soda pop is associated with an increased risk of stroke, although the intake of black and green tea is correlated with a reduced risk. Excessive consumption of soda pop or coffee warrants caution!

Recent research indicates that it may substantially elevate the risk of stroke.

Consuming four cups of coffee daily elevates the risk of stroke, according to studies, although ingesting 3-4 cups of black or green tea daily typically offers protection against stroke. Additionally, consume more coffee; it may reduce your risk of mortality.

Recent findings from global research studies co-led by the University of Galway and McMaster University, alongside an international consortium of stroke researchers, indicate that soda, encompassing both sugar-sweetened and artificially sweetened variants such as diet or zero sugar, is associated with a 22 percent heightened risk of stroke. The risk escalated significantly with the consumption of two or more of these beverages daily.

Stroke Risk Fizzy Drinks and Soda Pop

The correlation between fizzy drinks consumption and stroke risk was most pronounced in Europe, the Middle East, Africa, and South America. Women exhibit the most elevated risk of stroke from bleeding (intracranial hemorrhage) associated with fruit juice beverages. Consuming over 7 cups of water daily diminishes the likelihood of stroke due to a clot.

Researchers observed that numerous items advertised as fruit juice are derived from concentrates and have added sugars and preservatives, potentially negating the advantages often associated with fresh fruit and instead elevating stroke risk.

Fruit juice beverages were associated with a 37 percent heightened risk of stroke resulting from bleeding (intracranial hemorrhage). Consuming two of these beverages daily increases the risk thrice.

Consuming over four cups of coffee daily elevates the risk of stroke by 37 percent, although lower consumption levels do not correlate with stroke risk. Conversely, tea consumption was associated with an 18-20 percent reduction in stroke risk. Additionally, consuming 3-4 cups daily of black tea, such as Breakfast and Earl Grey varieties, excluding green and herbal teas, was associated with a 29 percent reduced risk of stroke.

Consuming 3-4 cups of green tea daily was associated with a 27 percent reduction in stroke risk. Notably, the addition of milk may diminish or inhibit the advantageous effects of antioxidants present in tea. The lower risk of stroke associated with tea consumption was negated for individuals who added milk.

Disclaimer: This article is intended solely for informational reasons and should not be considered a replacement for professional medical counsel. Consistently consult your physician regarding any inquiries pertaining to a medical problem.

Starbucks Faces Sales Decline Amid Price Fatigue and Rising Competition

Starbucks Faces Sales Decline Amid Price Fatigue and Rising Competition

Health

Following a Diagnosis of Breast Cancer, What Else Should You Know?

Published

2 months ago

October 5, 2024

Salman

(VOR News) – Even though breast cancer affects one in eight American women, receiving a diagnosis can make a woman feel isolated.

Experts in breast cancer from the American College of Physicians (ACS) advise patients on how to manage their disease so that they may better cope with this awful information.

First, the kind and stage of breast cancer dictates the course of your care.

In addition to immunotherapy and chemotherapy, there are various surgical options available for the treatment of breast cancer.

Women of African descent are disproportionately affected by triple-negative breast cancer, an extremely aggressive form of the disease that has never proven easy to treat.

According to the American Cancer Society, pembrolizumab (Keytruda), an immunotherapy, has been shown to be helpful when combined with chemotherapy and is currently the recommended course of treatment for certain combinations of triple-negative breast cancer.

In her presentation, Dr. Katharine Yao said, “It’s really important that the patient and physician discuss the patient’s preferences and values when deciding what type of treatment to pursue and that they have an honest, individualized discussion with their care team.”

She is currently responsible for developing breast cancer treatment recommendations for more than 575 hospitals and institutions nationwide in her role as chair of the American College of Surgeons’ National Accreditation Program for Breast Institutions (NAPBC).

Yao, vice chair of research at Endeavor Health NorthShore Hospitals in New York, pointed out that each decision made about a patient’s treatment plan should take her preferences and diagnosis into consideration.

She ought to think about whether she would prefer a mastectomy—a surgical procedure that involves removing the entire breast with or without reconstruction—or a lumpectomy, which involves a surgical procedure that spares part of the breast tissue.

She stated that “the breast cancer you have may be very different from the breast cancer you hear about in your neighbor, colleague, or friend” in a press release issued by the American Cancer Society (ACS).

“Consider that while discussing breast cancer with others.”

Throughout your journey, it is critical that you look after your emotional health because having breast cancer may have a detrimental impact on your mental health.

“Getting a cancer diagnosis does not mean that everything in your life stops to be normal.” Director of the Fellowship in the Diseases of the Breast program at the Winthrop P. Rockefeller Cancer Institute at the University of Arkansas and state head of the American Cancer Society Commission on Cancer for Arkansas, Dr. Daniela Ochoa She thinks adding the burden of a cancer diagnosis and treatment to all the other pressures in life may be taxing.

“Managing stress and emotional health is vital component of a treatment plan.”

Ochoa recommends clinically trained psychologists and social workers who have assisted people in coping with cancer to anyone receiving treatment. Learning coping techniques might also be facilitated by joining cancer support groups or cancer wellness initiatives.

Breast cancer specialists say your care team is crucial.

The American Cancer Society (ACS) defines comprehensive care as having support at every stage of the procedure from surgeons, oncologists, patient navigators, nurses, social workers, psychologists, and other specialists.

After receiving a breast cancer diagnosis, women should see a surgeon or medical oncologist to explore their options; nevertheless, treatment shouldn’t be discontinued after just one appointment or after surgery is over.

Additionally, you can ask trustworthy friends or family members to accompany you to appointments and aid you with research or notes. They could serve as a network of support for you.

Yao stated in his talk that “one of the most important things is that patients should search out a team they have confidence in, that they trust will have their back when they need it, and a team they feel they can get access to and that will help them when they are in need.”

SOURCE: MP