Health

Expert Reveals Why Thailand Chose the AstraZeneca Covid-19 Vaccine

Virology expert Dr Yong Poovorawan, has told a Public Health Ministry briefing to explain why Thailand chose AstraZeneca’s covid-19 vaccine. Dr Yong is chief of the Centre of Excellence in Clinical Virology at Chulalongkorn University, appeared at a Public Health Ministry briefing in a bid to reassure the public after widespread concern over Thailand’s Covid-19 vaccine procurement.

“It is impossible for [every country] to get vaccines immediately even when they have enough money,” Dr Yong explained. “The global population is more than 7 billion. Just 50 per cent of population would need 8 billion vaccines since each person has to take two doses. So it will be impossible to vaccinate everybody within this year.”

How long before vaccine is approved – and will it be safe?

Vaccines usually take a long time to develop in animal and clinical (human) trials, which first need approval from the Food and Drug Administration (FDA), said Yong.

Clinical trials have three steps: safety study, immunity test and effectiveness study. The final step usually takes more than a year or two for researchers to collect data from parallel trials where one group of volunteers is given the vaccine and a parallel “control” group is given a placebo.

However, that process has been accelerated as scientists around the world hurried to find a cure for the global pandemic.

As a result, Covid-19 vaccines have been developed in just one year. They are now being screened for safety and efficacy by health authorities globally, including Thailand’s FDA.

Sinovac or AstraZeneca: Which is better?

We need to see which vaccines Western countries are using, said Dr Yong. The first available were mRNA vaccines – a new type of vaccine to protect against infectious diseases. These vaccines use strands of genetic material called mRNA inside a special coating called a nanoparticle.

When injected, they instruct the human body to create a “spike protein” similar to the SARS-CoV-2 virus responsible for Covid-19. This immune response produces antibodies to protect our cells from getting infected if the virus enters our body.

We could say it uses our body to create a vaccine, said Yong. The mRNA method is new for humans but draws on previous research on other diseases.

Another type is the viral vector vaccines produced by AstraZeneca and Russia’s Sputnik programme. These are similar to mRNA vaccines but use adenovirus as a vector instead of nanoparticles. This vaccine technology has a proven track record fighting the spread of Ebola in Africa. Moreover, viral vector vaccines will be cheaper in the future.

China’s Sinovac uses a third approach – the inactivated or killed vaccine method that has been in use for 70 years to combat viruses such as polio and rabies. The disadvantage of this vaccine is difficulty in manufacturing, increased cost per dose, and multiple immunizations required.

Thailand has agreed to buy two million doses of SinoVac’s inactivated vaccine. As we know almost everything about traditional inactivated vaccines, it would be easier to handle, said Yong. But its relatively high cost of manufacturing makes it difficult to produce and purchase in high quantities.

Side effects of vaccine in Norway

The deaths might have been caused by side effects such as dizziness that triggered accidents, he said.

Norwegian health authorities say common adverse reactions to mRNA vaccines that are not usually dangerous – such as fever, nausea and diarrhoea – may have played a role in the deaths. Dr Yong pointed out that death rates in general among the elderly had not risen after vaccination.

Will pregnant women and children get the jab?

Dr Yong said more research was needed on safety and dosage before pregnant women and children under 18 were given the vaccine in Thailand.

Addressing public calls to vaccinate people of working age first, he said there was no guarantee this move would prevent transmission.

He explained that the vaccine may just prevent symptoms, meaning that even if they were inoculated, the working-age group could spread the virus to at-risk members of society.

People should understand that every disease can be prevented, Dr Yong said in conclusion. Vaccines were just one tool to help stop the virus from spreading.

Meanwhile people should calmly continue using the tools in hand – keep their hands clean, wearing masks, and social distancing – to protect themselves. The results of vaccination would be seen soon, he predicted, since many wealthy countries had already rolled out inoculation programmes.

Source: Asia One

Health

Report Causes Pfizer Stock to Climb Approximately $1 Billion Acquired by Starboard

(VOR News) – According to a rumor that activist investor Pfizer Starboard Value has taken a holding in the struggling pharmaceutical business that is expected to be worth around one billion dollars, the stock of Pfizer (PFE) is on the increase in premarket trading on Monday.

This comes after the report was made public. The report was made available to the general public following this. Starboard Value was successful in moving forward with the acquisition of the position.

Starboard is said to have approached Ian Read, a former chief executive officer of Pfizer, and Frank D’Amelio, a former chief financial officer, in order to seek assistance with its goals of boosting the performance of the company, according to the Wall Street Journal. Read and D’Amelio are both former Pfizer executives.

The purpose of this is to facilitate the accomplishment of its objectives, which include enhancing the overall performance of the firm.

In their previous jobs, D’Amelio and Read were chief financial officers.

It is stated in the report that the hedge fund is of the opinion that Pfizer, which is currently being managed by Albert Bourla, who succeeded Read as Chief Executive Officer (CEO) in 2019, does not demonstrate the same level of mergers and acquisitions (M&A) discipline that Read did. Bourla took over for Read in 2019. Read was succeeded by Bourla in the year 2019.

Pfizer, a multinational pharmaceutical conglomerate, has made substantial investments in the acquisition of more companies that are involved in the research and development of cancer medicines.

These businesses have been acquired for billions of dollars. The biotechnology company Seagen, which was acquired by Pfizer in the previous year for a price of $43 billion, is included in this category. One of the businesses that can be classified as belonging to this category is Seagen.

In spite of the fact that the S&P 500 Index experienced a 21% increase in 2024.

No major trading occurred in Pfizer stock that year.

Due to the fact that the demand for Pfizer’s COVID-19 vaccines fell after the firm reached its pandemic peak in 2021, the share price of the corporation has decreased by over fifty percent since that time.

This drop has occurred ever since the company’s shares reached their maximum peak, which was during the time that this decline occurred. Not only have they not changed at all, but they have also remained essentially stable. This is in contrast to the S&P 500, which has gained 21% since the beginning of this year.

Recently, the corporation was forced to take a hit when it decided to recall all of the sickle cell illness medications that it had distributed all over the world.

Fears that the prescription could lead patients to experience severe agony and possibly even death were the impetus for the decision to recall the product. In spite of the fact that Pfizer’s stock is increasing by almost three percent as a result of the news that followed the company’s decision, this is the circumstance that has come about.

SOURCE: IPN

Health

New Study Reveals Drinking Soda Pop Increases the Risk of Stroke

If you drink too much soda, fruit juice and coffee, beware!

A recent report from global research indicates that excessive consumption of coffee or soda pop is associated with an increased risk of stroke, although the intake of black and green tea is correlated with a reduced risk. Excessive consumption of soda pop or coffee warrants caution!

Recent research indicates that it may substantially elevate the risk of stroke.

Consuming four cups of coffee daily elevates the risk of stroke, according to studies, although ingesting 3-4 cups of black or green tea daily typically offers protection against stroke. Additionally, consume more coffee; it may reduce your risk of mortality.

Recent findings from global research studies co-led by the University of Galway and McMaster University, alongside an international consortium of stroke researchers, indicate that soda, encompassing both sugar-sweetened and artificially sweetened variants such as diet or zero sugar, is associated with a 22 percent heightened risk of stroke. The risk escalated significantly with the consumption of two or more of these beverages daily.

Stroke Risk Fizzy Drinks and Soda Pop

The correlation between fizzy drinks consumption and stroke risk was most pronounced in Europe, the Middle East, Africa, and South America. Women exhibit the most elevated risk of stroke from bleeding (intracranial hemorrhage) associated with fruit juice beverages. Consuming over 7 cups of water daily diminishes the likelihood of stroke due to a clot.

Researchers observed that numerous items advertised as fruit juice are derived from concentrates and have added sugars and preservatives, potentially negating the advantages often associated with fresh fruit and instead elevating stroke risk.

Fruit juice beverages were associated with a 37 percent heightened risk of stroke resulting from bleeding (intracranial hemorrhage). Consuming two of these beverages daily increases the risk thrice.

Consuming over four cups of coffee daily elevates the risk of stroke by 37 percent, although lower consumption levels do not correlate with stroke risk. Conversely, tea consumption was associated with an 18-20 percent reduction in stroke risk. Additionally, consuming 3-4 cups daily of black tea, such as Breakfast and Earl Grey varieties, excluding green and herbal teas, was associated with a 29 percent reduced risk of stroke.

Consuming 3-4 cups of green tea daily was associated with a 27 percent reduction in stroke risk. Notably, the addition of milk may diminish or inhibit the advantageous effects of antioxidants present in tea. The lower risk of stroke associated with tea consumption was negated for individuals who added milk.

Disclaimer: This article is intended solely for informational reasons and should not be considered a replacement for professional medical counsel. Consistently consult your physician regarding any inquiries pertaining to a medical problem.

Starbucks Faces Sales Decline Amid Price Fatigue and Rising Competition

Starbucks Faces Sales Decline Amid Price Fatigue and Rising Competition

Health

Following a Diagnosis of Breast Cancer, What Else Should You Know?

(VOR News) – Even though breast cancer affects one in eight American women, receiving a diagnosis can make a woman feel isolated.

Experts in breast cancer from the American College of Physicians (ACS) advise patients on how to manage their disease so that they may better cope with this awful information.

First, the kind and stage of breast cancer dictates the course of your care.

In addition to immunotherapy and chemotherapy, there are various surgical options available for the treatment of breast cancer.

Women of African descent are disproportionately affected by triple-negative breast cancer, an extremely aggressive form of the disease that has never proven easy to treat.

According to the American Cancer Society, pembrolizumab (Keytruda), an immunotherapy, has been shown to be helpful when combined with chemotherapy and is currently the recommended course of treatment for certain combinations of triple-negative breast cancer.

In her presentation, Dr. Katharine Yao said, “It’s really important that the patient and physician discuss the patient’s preferences and values when deciding what type of treatment to pursue and that they have an honest, individualized discussion with their care team.”

She is currently responsible for developing breast cancer treatment recommendations for more than 575 hospitals and institutions nationwide in her role as chair of the American College of Surgeons’ National Accreditation Program for Breast Institutions (NAPBC).

Yao, vice chair of research at Endeavor Health NorthShore Hospitals in New York, pointed out that each decision made about a patient’s treatment plan should take her preferences and diagnosis into consideration.

She ought to think about whether she would prefer a mastectomy—a surgical procedure that involves removing the entire breast with or without reconstruction—or a lumpectomy, which involves a surgical procedure that spares part of the breast tissue.

She stated that “the breast cancer you have may be very different from the breast cancer you hear about in your neighbor, colleague, or friend” in a press release issued by the American Cancer Society (ACS).

“Consider that while discussing breast cancer with others.”

Throughout your journey, it is critical that you look after your emotional health because having breast cancer may have a detrimental impact on your mental health.

“Getting a cancer diagnosis does not mean that everything in your life stops to be normal.” Director of the Fellowship in the Diseases of the Breast program at the Winthrop P. Rockefeller Cancer Institute at the University of Arkansas and state head of the American Cancer Society Commission on Cancer for Arkansas, Dr. Daniela Ochoa She thinks adding the burden of a cancer diagnosis and treatment to all the other pressures in life may be taxing.

“Managing stress and emotional health is vital component of a treatment plan.”

Ochoa recommends clinically trained psychologists and social workers who have assisted people in coping with cancer to anyone receiving treatment. Learning coping techniques might also be facilitated by joining cancer support groups or cancer wellness initiatives.

Breast cancer specialists say your care team is crucial.

The American Cancer Society (ACS) defines comprehensive care as having support at every stage of the procedure from surgeons, oncologists, patient navigators, nurses, social workers, psychologists, and other specialists.

After receiving a breast cancer diagnosis, women should see a surgeon or medical oncologist to explore their options; nevertheless, treatment shouldn’t be discontinued after just one appointment or after surgery is over.

Additionally, you can ask trustworthy friends or family members to accompany you to appointments and aid you with research or notes. They could serve as a network of support for you.

Yao stated in his talk that “one of the most important things is that patients should search out a team they have confidence in, that they trust will have their back when they need it, and a team they feel they can get access to and that will help them when they are in need.”

SOURCE: MP